In some texts, the term is also used to describe the condition of a rigid, nondistensible stomach which may be caused by a nonmalignant condition such as a caustic injury to the stomach. The histological and immunohistochemical studies of samples confirmed the presence of gastric metastases from breast carcinoma. She went to sloan ketterin in new york city, a top cancer center and to make a long story short, they were very cold, poor bedisde manner and she felt like a number, so she decided to go to my dads oncologist closer to her home for a 2nd opinion. Linitis plastica is a widely used term for brintons disease also known as leather bottle stomach, a morphological variant of diffuse or infiltrating stomach cancer.
Carcinoma of linitis plastica type involving the intestine. Endoscopic ultrasonographic features of gastric linitis. Adenocarcioma is the most common form of stomach cancer. Linitis plastica is a diffuse infiltrative gastric adenocarcinoma. All patients underwent a total gastrectomy, 45 patients even.
N2 linitis plastica is a rare complication of adenocarcinoma and can affect a variety of organs. Las tres neoplasias gastricas malignas primarias mas comunes son adenocarcinoma 95%, linfoma gastrico 4%. Gastrectomy specimen showed diffusely thickened stomach with macroscopic appearance of linitis plastica figure 1. Linitis plastica is a descriptive term usually referring to the appearance of the stomach, although the rectum can also be described this way.
Gastric linitis plastica is a very particular malignant gastric tumor different from the usual gastric adenocarcinoma. Cect abdomen showed evidence of thickened stomach with perigastric small lymph nodes. The neoplasm is encountered in every segment of gastrointestinal tract. Jun 30, 2011 the role of surgery for gastric linitis plastica glp is questioned. The operative findings showed linitis plastica of the stomach. Jan 27, 2011 treatment options for patients with diffuse type gastric cancer linitis plastica are discussed controversial. She had been in and out of the er for approximately a month, complaining of intense stomach pains all around her abdominal region, as well as the inability to finish her meals or keep any food down without vomiting or extreme nausea. Pdf on feb 1, 2009, l adan merino and others published unusual diagnosis of gastric linitis plastica find. Pdf unusual diagnosis of gastric linitis plastica researchgate. Harisankar cn, kashyap r, bhattacharya a, mittal br. Linitis plastica definition of linitis plastica by medical. Prognostic factors in patients with diffuse type gastric. This study aimed to analyze our experience in the surgical treatment of glp with specific reference to the resectability rate, prognosis, and mode of recurrence. The role of surgery for gastric linitis plastica glp is questioned.
The objective of this study was to investigate the endosonographic appearance of gastric linitis plastica glp and to study the usefulness of endoscopic ultrasonography eus for the t and n staging of glp. Gastric or stomach linitis plastica is the medical term for a rare type of stomach gastric cancer. In all patients, eus showed that lesions involved at least onethird of the circumference of. It is sometimes discussed that these patients should be treated primarily in palliative intention conservative without resection. In a singlecenter analysis, we investigated 120 patients with diffuse type gastric cancer. Oct 07, 2012 endoscopy of linitis plastica stomach cancer linitis plastica, also known leather bottle stomach, is a morphological variant of diffuse or infiltrating stomach cancer. Infiltrating gastric carcinomas cause wall thickening, luminal narrowing, and loss of pliability secondary to. Gastric cancers that occur in this syndrome are of the diffuse type as opposed to intestinal and often have signet ring cells through the stomach wall causing thickening linitis plastica without forming a discrete mass. Most of the patients presenting with symptoms have an advanced form of the disease, with the reason being the limited sensory qualities of the stomach. Her father died at age 91 with a prostate tumor diagnosed 17 years before and her mother was still alive 89 years without tumoral disease. Linitis plastica diagnosis, linitis plastica surgery, adenocarcinoma keywords. Gastric outlet obstruction secondary to linitis plastica of. Linitus plastica is rare and prognosis is usually very bad.
Gastric linitis plastica article pdf available in video journal and encyclopedia of gi endoscopy 11. Adenocarcinoma gastrico padrao linite plastica by jorge. Abstract gastric cancer has a pattern of presentation ranging from early stage to linitis plastica, with radically different prognosis. Endoscopy of linitis plastica stomach cancer linitis plastica, also known leather bottle stomach, is a morphological variant of diffuse or infiltrating stomach cancer. All patients underwent a total gastrectomy, 45 patients even a. My husband is a one year 3 month survivor of stage iii linitis plastica. We werent told the name of the cancer until 2 days before his surgery. Linitis plastica refers to the diffuse proliferation of the connective tissue, resulting in tissue thickening so that the stomach is constricted and rigid. Linitis plastica of the stomach rojoson medical clinic. Advanced gastric cancer linitis plastica presented with disseminated intravascular coagulation.
Hereditary diffuse gastric cancer hdgc stanford health care. Its diagnosis requires morphology findings of an infiltrating stomach tumor and pathology findings including signetring cells and fibrous. Treatment options for patients with diffuse type gastric cancer linitis plastica are discussed controversial. The diagnosis of gastric metastases of breast cancer requires a high index of suspicion, due to the non. My motherinlaw was diagnosed about a month ago with this rare linitis plastica stomach cancer. Video endoscopic sequence 5 of the image and video een some typical parameters of criteria of a malign ulcer. Typically, this entity shows slow progression and insidious clinical course. All stage iv metastatic linitis plastica gastric cancer messages. Aguilar estrada, nayeli salazar, yunuen villanuea, antonio g. Most of the patients presenting with symptoms have an advanced form of the disease, with the. Linitis plastica accounts for 319% of gastric cancers.
The neoplasm is encountered in every segment of gastrointestinal tract, with the gastric localization being the most frequent. Linitis plastica lp denotes a diffuse, intramurally infiltrating, primary or secondary anaplastic adenocarcinoma in a hollow structure, resulting in a shrunken organ with thickened walls. Jun 25, 20 gastric linitis plastica is a diffuse type of cancer in which the cells invade throughout the stomach, resulting in the thickening and rigidity of the stomach wall. My husbands surgeon considered the total gastrectomy palliative i. The appearance is said to be reminiscent of an old leather waterbottle. Linitis plastica carcinoma of stomach with extensive metastases simulating colonic lesion. The patient had undergone gastrectomy in view of gastric outlet symptoms and had significant anorexia and weight loss. I have not been able to find any stories of a survivor either, but believe that the current treatments can work either for a while until better treatments are discovered or as a possible cure. Eus examinations of 55 patients with histologically proven glp were retrospectively studied. Fluorodeoxyglucose positron emission tomographycomputed tomography patt ern in a patient with linitis plastica of the stomach caused by primary signet cell adenocarcinoma. A high index of suspicion must be present when this appearance is identified, as mucosal biopsies are often negative and deeper biopsies are required to make. Gastric cancer has a pattern of presentation ranging from early stage to. Linitis plastica represents a diffuse process within the gastric body of enlarged, often edematous and erythematous, folds with poor distensibility of the gastric wall with insufflation. Linitis plastica linitis plastica is a form of gastric narrowing caused by chronic inflammation, infection, or trauma, but is most often directly associated with malignancy.
A few days ago, my mother was diagnosed with stage iv linitis plastica gastric cancer. Results of surgery were analyzed in 102 patients with glp. She had been in and out of the er for approximately a month, complaining of intense stomach pains all around her abdominal region, as well as the inability to finish her meals or. Of the 102 patients, 92 underwent surgical exploration, with resection performed in 60 cases. Linitis plastica is a malignant disease that usually occurs in the stomach, although it can affect any segment of the alimentary tract. My husband tony was diagnosed with linitis plastica 2 years ago. Gastric linitis plastica is a diffuse type of cancer in which the cells invade throughout the stomach, resulting in the thickening and rigidity of the stomach wall. T1 gastric outlet obstruction secondary to linitis plastica of the stomach as shown on transabdominal sonography.732 434 1311 172 281 1495 1425 278 1203 970 1089 761 1107 250 630 1434 1139 963 1250 1253 407 737 602 1326 1113 369 165 1108 716 509 1070 1472 423 1485 940 21 980 674 663 96 998 610 1061 289 775 728 666